481 Lipoperoxidation and vitamin C status in psoriasis

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Assessment of vitamin C status.

Vitamin C is L-xyloascorbic acid (ascorbic acid, AA). Its first oxidation product is dehydroascorbic acid (dehydroAA) which also possesses vitamin C activity, possibly because of the ease with which many animal tissues can reduce it back to AA (Grimble & Hughes, 1967). AA and dehydroAA may be referred to as ‘total vitamin C’. T h e determination of AA, or of AA and dehydroAA, is central to all ...

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Agreement among indicators of vitamin C status.

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Phototherapy (broadband UVB, narrowband UVB (NBUVB) and heliotherapy – treatment with natural sunlight) is a commonly used treatment modality for widespread psoriasis. A similar wavelength spectrum of UVB (280-315 nm) is responsible for vitamin D synthesis in the skin. Vitamin D3, or cholecalciferol, is produced from 7-dehydrocholesterol in the basal epidermis when exposed to UVB, and is then h...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2017

ISSN: 0022-202X

DOI: 10.1016/j.jid.2017.07.677